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Viral Packaging Services

Ready-to-transduce lentiviral and AAV particles, packaged from your construct or ours

Getting from a construct to usable virus should be straightforward. This service packages ready-to-transduce lentiviral and AAV particles through partners with years of experience in viral production. You can send your own construct, or have a ready-made one packaged, for expression, knockdown, or screening work. Custom lentiviral expression constructs, sgRNA constructs, and pooled libraries can all be produced. Custom AAV packaging runs through abm, with a choice of serotype (1 to 11, AAV2/8, AAV2/9n, AAV2.7m8, PHP.eB, PHP.S, shH10, and Anc80L65) and three purification grades covering cell culture and in vivo work. Where your construct itself still has to be built, the custom cloning services page covers the design and cloning step that feeds into packaging.

What you can package

1. Expression particles. You can have a gene of interest packaged for stable or transient overexpression in dividing and non-dividing cells.

2. Knockdown and knockout. shRNA or CRISPR sgRNA constructs get packaged for loss-of-function studies.

3. Pooled libraries. sgRNA or shRNA library preparations are produced for genome-wide screens.

4. Your construct or ours. You can supply a plasmid, or have a construct built and packaged in one step.

Applications

Stable cell line generation

Lentiviral integration gives long-term expression, a fast route to stable lines with lentiviral expression systems.

Hard-to-transfect cells

Lentivirus transduces primary cells, stem cells, and non-dividing cells that resist standard transfection.

Gene knockdown and knockout

Packaged shRNA or CRISPR sgRNA delivers loss-of-function tools into your model system.

Pooled genetic screens

Library-scale packaging supports genome-wide screens with a downstream NGS readout.

Reporter and tracing studies

Fluorescent or luminescent reporters delivered by lentivirus track cells over time.

Overexpression models

Stable transgene expression drives pathway and phenotype studies, alongside other viral expression systems.

In vivo AAV delivery

Ultra-Pure AAV is purified by ultracentrifugation for animal work, and the serotype you select sets the tissue tropism your study gets.

Frequently asked questions

Can I send my own construct?

Yes. Send a ready-made plasmid for packaging, or have a construct built and packaged in one step.

What can be packaged?

Lentiviral expression constructs, shRNA and CRISPR sgRNA constructs, and pooled sgRNA or shRNA libraries can all be produced. Custom AAV is packaged by abm across serotypes 1 to 11 and a set of engineered variants including PHP.eB, PHP.S, shH10, and Anc80L65, in three purification grades.

Which cells can the particles transduce?

Lentiviral particles transduce both dividing and non-dividing cells, including primary cells and stem cells that are hard to transfect by other methods. For AAV, transduction follows from the serotype you select, and abm recommends consulting literature covering your target tissue and testing more than one serotype where that is practical.

Product catalogs

Not sure which catalog to start with? We will help you find the right products.

Tell us what you are looking for — antibodies, kits, proteins, or supplies — and our team will point you to the best catalog filters, suppliers, and product matches for your workflow.

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