EXTRAClean Plasma/Serum RNA Purification Mini Kit

• EXTRAClean RNA quality is specially tailored for NGS applications/RNA-seq
• Versatile plasma/serum input ranges
• No phenol extractions
• Fast and easy processing of samples for the purification and the isolation of RNA
• No time-consuming ultracentrifugation
• More effective than any other method
• EXTRAClean resin separation matrix provides highly purified RNA

Norgen's EXTRAClean Plasma/Serum Cell-Free Circulating RNA Purification Mini Kit provides a fast, reliable and convenient method to purify and concentrate high quality, high purity and inhibitor-free cell-free circulating and exosomal RNA using a convenient spin column method. The kit can purify RNA from fresh or frozen serum or plasma samples prepared from blood collected on either EDTA or Citrate. Plasma samples prepared from blood collected on heparin should not be used, as heparin can significantly interfere with many downstream applications such as RT-PCR. The purified plasma/serum RNA is fully compatible with all downstream applications including PCR, qPCR, methylation-sensitive reverse transcription qPCR, reverse transcription PCR, Northern blotting, RNase protection and primer extension, expression array assays, and NGS. The EXTRAClean columns undergo stringent processing and rigorous quality control measures to minimize contamination traces, ensuring optimal results for sensitive applications such as NGS.

Kit Specifications

Supporting Data

Figure 1. Average small RNA biotype distribution relative to the input reads obtained from sequencing of cell-free RNA plasma samples using Plasma/Serum RNA Purification kits.