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Hybridisation Capture (myBaits)

myBaits hybridisation capture probes for targeted sequencing enrichment before NGS

When you need to enrich target regions from a sequencing library before NGS, hybridisation capture uses biotinylated bait probes to pull them out. The workhorse for targeted sequencing in ancient DNA, low-input forensic samples, phylogenomics, and pathogen surveillance.

Pick by panel and chemistry.

  1. Panel. Catalogue panels for human exome, ultraconserved elements, plant chloroplast, and many model organisms. Custom design supports any user-specified region.
  2. Bait length and tiling. Longer and denser tiling improves capture from degraded DNA but raises cost.
  3. Bait chemistry. RNA baits give higher specificity at cost of stability. DNA baits are more robust.
  4. Sample. Ancient DNA needs high-sensitivity dense tiling. Modern samples need standard protocol on more samples in parallel.

Arbor Biosciences is the sole supplier in this inventory.

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