Simoa reaches femtogram per millilitre levels, roughly 1000 times more sensitive than a standard sandwich ELISA, which is typically limited to picogram per millilitre detection.
Services
Single Molecule Array (Simoa) Testing Service
Ultrasensitive Simoa protein detection service for low-abundance biomarkers in complex samples
Some biomarkers sit below what a standard ELISA can see. Simoa, or single molecule array detection, reaches femtogram per millilitre sensitivity, around 1000 times lower than a conventional sandwich immunoassay, so you can measure proteins that were previously out of range. The RayBiotech Ultrasensitive Simoa Testing Service runs your samples on a dedicated Simoa analyser, so you get the data without owning the instrument. You ship your samples and the team performs the assay and returns a full data report.
Simoa isolates single immunocomplexes on paramagnetic beads using standard ELISA reagents, then traps individual beads in femtolitre-sized wells for a digital, molecule-by-molecule readout. That digital counting is what pushes the detection limit far below an analogue ELISA.
Applications
- Low-abundance proteins. Targets sitting at femtogram to picogram levels in a sample fall well below the detection floor of a standard sandwich ELISA.
- Low-volume and precious samples. Limited serum, plasma, CSF, and other complex matrices return usable data, so your material does not have to be pooled before the run.
- Multiplex panels. Up to 4 analytes are quantified in a single run, which conserves your sample volume and shortens the time each cohort spends in the assay.
- Ship-and-report workflow. Your samples go to the GLP-compliant lab and a validated protein quantification report comes back, with no Simoa instrument on site.
Services
Request Protein Detection and Quantification Services
Please enter your request information and personal data. Once we receive your request, we will review it and send you a detailed quote.
Frequently asked questions
Serum, plasma, CSF, and other complex matrices all work, and the method suits low-volume samples.
Multiplexing is available for up to 4 analytes per run.
No. You ship your samples and RayBiotech performs the assay and returns the data report.
Product catalogs
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Tell us what you are looking for — antibodies, kits, proteins, or supplies — and our team will point you to the best catalog filters, suppliers, and product matches for your workflow.
