SKU: T68870-100mg-TM
SU-11752
Blue Ice
Specifications
| Specification | Details |
|---|---|
| CAS No. | 688036-19-3 |
| Additional Information | SU-11752 is a potent and selective DNA-PK inhibitor. Inhibition kinetics and a direct assay for ATP binding showed that SU11752 inhibited DNA-PK by competing with ATP. SU11752 inhibited DNA double-strand break repair in cells and gave rise to a five-fold sensitization to ionizing radiation. At concentrations of SU11752 that inhibited DNA repair, cell cycle progression was still normal and ATM kinase activity was not inhibited. |
| Molecular Weight | 493,57468 |
| Formula | C26H27N3O5S |
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Catalog Number
T68870-100mg-TM
Name
SU-11752
Price(100 mg)
Pack Size