SKU: PDER100248-100ug-ELS
Recombinant Rat TNF-α Protein(Sumo Tag)
Rat
In Stock
Blue Ice
Specifications
| Specification | Details |
|---|---|
| Molecular Weight | 30.0 kDa |
| Tag | N-Sumo |
| Source | E.coli |
| Purity | > 95% as determined by reducing SDS-PAGE. |
| Endotoxin Level | < 10 EU/mg of the protein as determined by the LAL method |
| Format | Lyophilized from a 0.2 μm filtered solution in PBS with 5% Trehalose and 5% Mannitol. |
| Synonyms | Tumor necrosis factor, Cachectin, TNFSF2 |
| Organism | Rat |
| Accession No. | P16599 |
| Sequence Info | Leu80-Leu235 |
| Background | Tumor necrosis factor alpha (TNF-alpha), also known as TNF, TNFA or TNFSF2, is the prototypic cytokine of the TNF superfamily, and is a multifunctional molecule involved in the regulation of a wide spectrum of biological processes including cell proliferation, differentiation, apoptosis, lipid metabolism, and coagulation. Two receptors, TNF-R1 (TNF receptor type 1; CD120a; p55/60) and TNF-R2 (TNF receptor type 2; CD120b; p75/80), bind to TNF-alpha. TNF-alpha protein is produced mainly by macrophages, and large amounts of this cytokine are released in response to lipopolysaccharide, other bacterial products, and Interleukin-1 (IL-1). TNF-alpha is involved in fighting against the tumorigenesis, thus, is regarded as a molecular insight in cancer treatment. |
Resources
PDF
Datasheet
Catalog Number
PDER100248-100ug-ELS
Name
Recombinant Rat TNF-alpha Protein(Sumo Tag)
Price(10000 ug)
Pack Size