SKU: PKSR030414-100ug-ELS
Recombinant Rat GPT2 Protein (His Tag)
Rat
In Stock
RT
Specifications
| Specification | Details |
|---|---|
| Molecular Weight | 55 kDa |
| Tag | C-His |
| Source | Baculovirus-Insect Cells |
| Purity | > 95 % as determined by reducing SDS-PAGE. |
| Endotoxin Level | < 1.0 EU per μg of the protein as determined by the LAL method |
| Format | Lyophilized from sterile 50mM Tris, 100mM NaCl, pH 8.0, 10% glycerol, 0.5mM TCEP |
| Synonyms | ALT2;Cc2-5;Gpt2 |
| Organism | Rat |
| Accession No. | NP_001012057.1 |
| Sequence Info | Met 1-Ser 522 |
| Background | Alanine aminotransferase (ALT), also known as glutamate pyruvate transaminase (Gpt), is a pyridoxal enzyme which catalyses the reversible interconversion of L-alanine and 2-oxoglutalate to pyruvate and L-glutamate, and plays a key role in the intermediary metabolism of glucose and amino acids. As a key enzyme for gluconeogenesis, Gpt is a widely-used serum marker for liver injury. Two ALT isoenzymes have been identified, ALT1 and ALT2 (GPT1 and GPT2), which are encoded by separate genes and share significant sequence homology, but differ in their expression patterns. Gpt1 is widely distributed and mainly expressed in intestine, liver, fat tissues, colon, muscle, and heart, in the order of high to low expression level, whereas Gpt2 expression is more restricted, mainly in liver, muscle, brain, and white adipose tissue. It has been reported that hepatic ALT2 protein is approximately four times higher in male rats than in female rats. |
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Datasheet
Catalog Number
PKSR030414-100ug-ELS
Name
Recombinant Rat GPT2 Protein (His Tag)
Price(10000 ug)
Pack Size
10000 ug