SKU: PKSM041157-50ug-ELS
Recombinant Mouse TSLP Receptor/CRLF2 Protein (His Tag)
Mouse
In Stock
RT
Specifications
| Specification | Details |
|---|---|
| Molecular Weight | 23.7 kDa |
| Tag | C-6His |
| Source | Human Cells |
| Purity | > 95 % as determined by reducing SDS-PAGE. |
| Endotoxin Level | < 1.0 EU per μg as determined by the LAL method. |
| Format | Lyophilized from a 0.2 μm filtered solution of 20mM PB, 150mM NaCl, pH 7.4. |
| Synonyms | CRL2; CRLF2; CRL2 cytokine receptor; Cytokine receptor-like 2; cytokine receptor-like factor 2; ILXR; IL-XR; P2RY8/CRLF2 fusion; Thymic stromal lymphopoietin protein receptor; Thymic stromal-derived lymphopoietin receptor; TSLP receptor; TSLPR |
| Organism | Mouse |
| Accession No. | Q8CII9 |
| Sequence Info | Ala20-Leu233 |
| Background | The cytokine thymic stromal lymphopoietin receptor (TSLPR) is consisting of a common γ receptor–like chain (TSLPR-γ) and a common interleukin 7 (IL-7) Rα chain that belongs to the type 1 cytokine receptor family. Transfection of TSLPR cDNA result in only low affinity binding, while cotransfection of the IL-7Rα chain cDNA shows high affinity binding. TSLP and TSLPR play a critical role in the initiation of allergic diseases in mice. The TSLP R cDNA encodes a transmembrane receptor containing 370 amino acids (aa) with two potential N-linked glycosylation sites and a cytoplasmic domain of 104 aa including a single tyrosine residue. TSLPR can mediate signaling of the signal transducer and activator of transcription 5 (Stat5) by TSLP. TSLP R is broadly expressed in the immune and hematopoietic cells, particularly in hematopoietic progenitors and myeloid cells. |
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Catalog Number
PKSM041157-50ug-ELS
Name
Recombinant Mouse TSLP Receptor/CRLF2 Protein (His Tag)
Price(5000 ug)
Pack Size