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SKU: PKSM040721-50ug-ELS

Recombinant Mouse Carbonic Anhydrase 4/CA4 Protein (His Tag)(Active)

Mouse In Stock RT

Specifications

Specification Details
Molecular Weight 31 kDa
Tag C-His
Source HEK293 Cells
Purity > 98 % as determined by reducing SDS-PAGE.
Endotoxin Level < 1.0 EU per μg of the protein as determined by the LAL method.
Activity Measured by its esterase activity. The specific activity is >10 pmoles/min/μg.
Format Lyophilized from sterile PBS, pH 7.4
Synonyms CA4;CAIV;CA-IV;Car4;Carbonate dehydratase IV;carbonic anhydrase 4;carbonic anhydrase IVRP17;carbonic dehydratase IV;EC4.2.1.1;retinitis pigmentosa 17;RP17
Organism Mouse
Accession No. NP_031633.1
Sequence Info Met 1-Ser 277
Background The carbonic anhydrases (or carbonate dehydratases) are classified as metalloenzyme for its zinc ion prosthetic group and form a family of enzymes that catalyze the rapid interconversion of carbon dioxide and water to bicarbonate and protons, a reversible reaction that takes part in maintaining acid-base balance in blood and other tissues. The carbonic anhydrasekl (CA) family consists of at least 11 enzymatically active members and a few inactive homologous proteins. Carbonic anhydrase IV (CAIV) is a membrane-associated enzyme anchored to plasma membrane surfaces by a phosphatidylinositol glycan linkage. CAIV is a high-activity isozyme in CO2 hydration comparable to that of CAII. Furthermore, CAIV is more active in HCO3- dehydration than is CAII. However, the esterase activity of CAIV is decreased 150-fold compared to CAII.

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Datasheet

Catalog Number
PKSM040721-50ug-ELS
Name
Recombinant Mouse Carbonic Anhydrase 4/CA4 Protein (His Tag)(Active)
Price(5000 ug)
Pack Size
5000 ug
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