SKU: RPC23562-1000-BM
Recombinant Mouse BAG family molecular chaperone regulator 3 (Bag3)
Mouse (Mus musculus)
Blue Ice
Specifications
| Specification | Details |
|---|---|
| Molecular Weight | 77.7kDa |
| Tag | N-Terminal 6Xhis-Sumo-Tagged |
| Source | E. coli |
| Purity | >90% by SDS-PAGE |
| Endotoxin Level | Not Tested |
| Synonyms | Bcl-2-associated athanogene 3Bcl-2-binding protein Bis |
| Organism | Mouse (Mus musculus) |
| Accession No. | Q9JLV1 |
| Sequence Info | Full Length of Mature Protein 2~577aa |
| Background | Co-chaperone for HSP70 and HSC70 chaperone proteins. Acts as a nucleotide-exchange factor (NEF) promoting the release of ADP from the HSP70 and HSC70 proteins thereby triggering client/substrate protein release. Nucleotide release is mediated via its binding to the nucleotide-binding domain (NBD) of HSPA8/HSC70 where as the substrate release is mediated via its binding to the substrate-binding domain (SBD) of HSPA8/HSC70. Has anti-apoptotic activity. Plays a role in the HSF1 nucleocytoplasmic transport. |
Catalog Number
RPC23562-1000-BM
Name
Recombinant Mouse BAG family molecular chaperone regulator 3 (Bag3)
Price(1000 ug)
Pack Size