SKU: RPC20327-20-BM
Recombinant Influenza A virus Hemagglutinin (HA), partial
Influenza A virus (strain A/Hickox/1940 H1N1)
Blue Ice
Specifications
| Specification | Details |
|---|---|
| Molecular Weight | 52.6kDa |
| Tag | N-Terminal 6Xhis-Sumo-Tagged |
| Source | E. coli |
| Purity | >90% by SDS-PAGE |
| Endotoxin Level | Not Tested |
| Synonyms | Cleaved into the following 2 chains:Hemagglutinin HA1 chainHemagglutinin HA2 chain |
| Organism | Influenza A virus (strain A/Hickox/1940 H1N1) |
| Accession No. | Q0HD60 |
| Sequence Info | Partial 18~343aa |
| Background | Binds to sialic acid-containing receptors on the cell surface, bringing about the attachment of the virus particle to the cell. This attachment induces virion internalization either through clathrin-dependent endocytosis or through clathrin- and caveolin-independent pathway. Plays a major role in the determination of host range restriction and virulence. Class I viral fusion protein. Responsible for penetration of the virus into the cell cytoplasm by mediating the fusion of the membrane of the endocytosed virus particle with the endosomal membrane. Low pH in endosomes induces an irreversible conformational change in HA2, releasing the fusion hydrophobic peptide. Several trimers are required to form a competent fusion pore. |
Catalog Number
RPC20327-20-BM
Name
Recombinant Influenza A virus Hemagglutinin (HA), partial
Price(20 ug)
Pack Size