SKU: PKSH031986-100ug-ELS
Recombinant Human/Mouse/Rat/Rhesus/Canine BMP-2 Protein (Active)
Human
RT
Specifications
| Specification | Details |
|---|---|
| Molecular Weight | 13 kDa |
| Source | E.coli |
| Purity | > 95 % as determined by reducing SDS-PAGE. |
| Endotoxin Level | Please contact us for more information. |
| Activity | Measured by its ability to induce alkaline phosphatase production by MC3T3-E1 mouse osteoblastic cells. The ED50 for this effect is typically 0.5-2 μg/ml. |
| Format | Lyophilized from sterile 30 % CAN, 0.1 % TFA, pH 2.9. |
| Synonyms | BDA2;BDA2A;BMP-2;BMP2A;BMP2 |
| Organism | Human |
| Accession No. | NP_001191.1 |
| Sequence Info | Gln283-Arg396 |
| Background | BMP-2 protein, like other bone morphogenetic proteins, plays an important role in the development of bone and cartilage. BMP-2 protein is involved in the hedgehog pathway, TGF beta signaling pathway, and cytokine-cytokine receptor interaction. BMP-2 and BMP-7 are osteogenic BMPs that have been demonstrated to potently induce osteoblast differentiation in a variety of cell types. BMP-2, BMP-4 and BMP-7 are known to be of major importance in bone formation and repair. In cancerous tissues BMP-2 protein may play an important role in the progression of glioma. |
Resources
PDF
Datasheet
Catalog Number
PKSH031986-100ug-ELS
Name
Recombinant Human/Mouse/Rat/Rhesus/Canine BMP-2 Protein (Active)
Price(100 ug)
Pack Size