SKU: PKSH033579-50ug-ELS
Recombinant Human TrkB/NTRK2 Protein (His Tag)(Active)
Human
In Stock
RT
Specifications
| Specification | Details |
|---|---|
| Molecular Weight | 45.25 kDa |
| Tag | C-His |
| Source | Human Cells |
| Purity | > 95 % as determined by reducing SDS-PAGE. |
| Endotoxin Level | < 1.0 EU per μg as determined by the LAL method. |
| Activity | Immobilized Human NT-3(Cat: PKSH032803) at 2μg/ml(100 μl/well) can bind Human TrkB-His. The ED50 of Human TrkB-His is 3.777ug/ml . |
| Format | Lyophilized from a 0.2 μm filtered solution of 20mM PB, 150mM NaCl, pH 7.2. |
| Synonyms | BDNF/NT-3 Growth Factors Receptor; GP145-TrkB; Trk-B; Neurotrophic Tyrosine Kinase Receptor Type 2; TrkB Tyrosine Kinase; Tropomyosin-Related Kinase B; NTRK2; TRKB |
| Organism | Human |
| Accession No. | Q16620 |
| Sequence Info | Cys32-His430 |
| Background | The TRK Family of Tyrosine Kinase Receptor consists of 3 members: TrkA, TrkB and TrkC. The three TRK family proteins have different ligand specificities. They connect to different neurotrophins, including NGF, BDNF, NT-3NT-4/5. TRKA binds NGF, TRKB binds BDNF and NT-3, TRKC binds NT-4/5. At the protein sequence level, human and rat TRKB have greater than 90% sequence identity and the proteins exbihit cross-species activity. TRKB is primarily expressed in the nervous system and it also expression in a wide variety of tissues with low levels. |
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Datasheet
Catalog Number
PKSH033579-50ug-ELS
Name
Recombinant Human TrkB/NTRK2 Protein (His Tag)(Active)
Price(5000 ug)
Pack Size