SKU: PDEH100779-100ug-ELS
Recombinant Human TNNC1 protein (His tag)
Human
In Stock
Blue Ice
Specifications
| Specification | Details |
|---|---|
| Molecular Weight | 17.6 kDa |
| Tag | N-His |
| Source | E.coli |
| Purity | > 95% as determined by reducing SDS-PAGE. |
| Endotoxin Level | < 10 EU/mg of the protein as determined by the LAL method. |
| Format |
Lyophilized from sterile PBS, pH 7.4. Normally 5%-8% trehalose, mannitol and 0.01% Tween 80 are added as protectants before lyophilization. Please refer to the specific buffer information in the printed manual. |
| Synonyms | CMD1Z;CMH13;TN-C;TNC;TNNC;Troponin C |
| Organism | Human |
| Accession No. | P63316 |
| Sequence Info | Met 1-Glu 161 |
| Background | Troponin I, also known as TNNC1, is part of the troponin complex. This complex contains 3 subunits: troponin I (TnI), troponin T (TnT) and troponin C (TnC). Troponin I is the inhibitory subunit, blocking actin-myosin interactions and thereby mediating striated muscle relaxation. It binds to actin in thin myofilaments to hold the actin-tropomyosin complex in place. Because of it myosin cannot bind actin in relaxed muscle. When calcium binds to the Troponin C it causes conformational changes which lead to dislocation of troponin I and finally tropomyosin leaves the binding site for myosin on actin leading to contraction of muscle. |
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Datasheet
Catalog Number
PDEH100779-100ug-ELS
Name
Recombinant Human TNNC1 protein (His tag)
Price(10000 ug)
Pack Size