SKU: RPC26068-20-BM
Recombinant Human Terminal nucleotidyltransferase 4B (TENT4B)
Human (Homo sapiens)
Blue Ice
Specifications
| Specification | Details |
|---|---|
| Molecular Weight | 67.3kDa |
| Tag | N-Terminal 6Xhis-Tagged |
| Source | E. coli |
| Purity | >85% by SDS-PAGE |
| Endotoxin Level | Not Tested |
| Synonyms | PAP-associated domain-containing protein 5 (Terminal nucleotidyltransferase 4B; Terminal uridylyltransferase 3; TUTase 3; Topoisomerase-related function protein 4-2; TRF4-2; GLD4; PAPD5; TRF4-2) |
| Organism | Human (Homo sapiens) |
| Accession No. | Q8NDF8 |
| Sequence Info | Full Length 1~572aa |
| Background | Catalytic subunit of a TRAMP-like complex which has a poly (A) RNA polymerase activity and is involved in a post-transcriptional quality control mechanism. Polyadenylation with short oligo (A) tails is required for the degradative activity of the exosome on several of its nuclear RNA substrates. Doesn't need a cofactor for polyadenylation activity (in vitro) . Plays a role in replication-dependent histone mRNA degradation, probably through terminal uridylation of mature histone mRNAs. May play a role in sister chromatid cohesion. |
Catalog Number
RPC26068-20-BM
Name
Recombinant Human Terminal nucleotidyltransferase 4B (TENT4B)
Price(20 ug)
Pack Size