SKU: PKSH032984-10ug-ELS
Recombinant Human PKLR Protein (His Tag)
Human
In Stock
Blue Ice
Specifications
| Specification | Details |
|---|---|
| Molecular Weight | 62.9 kDa |
| Tag | C-6His |
| Source | Human Cells |
| Purity | > 95 % as determined by reducing SDS-PAGE. |
| Endotoxin Level | < 1.0 EU per µg as determined by the LAL method. |
| Format | Supplied as a 0.2 μm filtered solution of 20mM Tris-HCl, 1mM DTT 0.2M NaCl, 10% glycerol, pH 8.0. |
| Synonyms | Pyruvate Kinase Isozymes R/L; Pyruvate Kinase 1; R-Type/L-Type Pyruvate Kinase; Red Cell/Liver Pyruvate Kinase; PKLR; PK1; PKL |
| Organism | Human |
| Accession No. | P30613 |
| Sequence Info | Met 1-Ser574 |
| Background | Pyruvate Kinase Isozymes R/L (PKLR) belongs to the pyruvate kinase family, There are 4 isozymes of pyruvate kinase in mammals: L, R, M1 and M2. L type is major isozyme in the liver; R is found in red cells; M1 is the main form in muscle, heart and brain; M2 is found in early fetal tissues. PKLR exists as a homotetramer and catalyzes the production of phosphoenolpyruvate from pyruvate and ATP. Defects in PKLR are also the cause of pyruvate kinase deficiency of red cells, which is a frequent cause of hereditary non-spherocytic hemolytic anemia. |
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Catalog Number
PKSH032984-10ug-ELS
Name
Recombinant Human PKLR Protein (His Tag)
Price(1000 ug)
Pack Size