SKU: PKSH032791-10ug-ELS
Recombinant Human NEDD8 Protein (His Tag, SUMO Tag)
Human
In Stock
RT
Specifications
| Specification | Details |
|---|---|
| Molecular Weight | 20.9 kDa |
| Tag | N-6His |
| Source | E.coli |
| Purity | > 95 % as determined by reducing SDS-PAGE. |
| Endotoxin Level | < 1.0 EU per µg as determined by the LAL method. |
| Format | Lyophilized from a 0.2 μm filtered solution of 20mM PB，150mM NaCl，5% Trehalose,pH7.4. |
| Synonyms | Neural precursor cell expressed developmentally down-regulated protein 8; NEDD8; Neddylin; Ubiquitin-like protein Nedd8; |
| Organism | Human |
| Accession No. | Q15843 |
| Sequence Info | Met 1-Gly76 |
| Background | Human NEDD8 shares 60% amino acid sequence identity to ubiquitin. The only known substrates of NEDD8 modification are the cullin subunits of SCF ubiquitin E3 ligases. The NEDDylation of cullins is critical for the recruitment of E2 to the ligase complex, thus facilitating ubiquitin conjugation. NEDD8 modification has therefore been implicated in cell cycle progression and cytoskeletal regulation. |
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Datasheet
Catalog Number
PKSH032791-10ug-ELS
Name
Recombinant Human NEDD8 Protein (His Tag, SUMO Tag)
Price(1000 ug)
Pack Size