SKU: PKSH033589-50ug-ELS
Recombinant Human METAP1 Protein
Human
In Stock
Blue Ice
Specifications
| Specification | Details |
|---|---|
| Molecular Weight | 43.2 kDa |
| Source | E.coli |
| Purity | > 95 % as determined by reducing SDS-PAGE. |
| Endotoxin Level | < 1.0 EU per μg as determined by the LAL method. |
| Format | Supplied as a 0.2 μm filtered solution of 20mM Tris,500mM NaCl,10%glycerol,pH8.0. |
| Synonyms | Methionine aminopeptidase 1; MAP 1; MetAP 1; Peptidase M 1; METAP1;MAP1A;MetAP1A |
| Organism | Human |
| Accession No. | P53582 |
| Sequence Info | Met1-Phe386 |
| Background | Methionine Aminopeptidase 1 is a member of the M24 family of metalloproteases. METAP1 plays an important role in G(2)/M phase regulation of the cell cycle and may serve as a promising target for the discovery and development of new anticancer agents. METAP1 and METAP2 have different substrate specificity due to the differences in both size and shape of the active sites. The proteolytic removal of N-terminal methionine from nascent peptides is catalyzed by a family of enzymes known as methionine aminopeptidases (MetAPs) and is essential for cell growth. Inhibition of METAPs provides a novel strategy in developing anti-cancer drugs. |
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Datasheet
Catalog Number
PKSH033589-50ug-ELS
Name
Recombinant Human METAP1 Protein
Price(5000 ug)
Pack Size