SKU: PKSH032623-50ug-ELS
Recombinant Human Interleukin-17F/IL-17F Protein
Human
RT
Specifications
| Specification | Details |
|---|---|
| Molecular Weight | 14.9 kDa |
| Source | Human Cells |
| Purity | > 95 % as determined by reducing SDS-PAGE. |
| Endotoxin Level | < 1.0 EU per µg as determined by the LAL method. |
| Format | Lyophilized from a 0.2 μm filtered solution of 20mM PB,150mM NaCl,pH7.4. |
| Synonyms | Interleukin-17F; IL-17F; Cytokine ML-1; Interleukin-24; IL-24; IL17F; IL24 |
| Organism | Human |
| Accession No. | Q96PD4 |
| Sequence Info | Arg31-Gln163 |
| Background | Interleukin-17F (IL-17F) exists in a disulfide-linked heterodimer that belongs to the IL-17 family. IL-17F is expressed in activated; but not resting; CD4+ T-cells and activated monocytes. IL-17F has been shown to stimulate the production of several other cytokines; including IL-6; IL-8; and granulocyte colony-stimulating factor. IL-17F can regulate cartilage matrix turnover and stimulates PBMC and T-cell proliferation. IL-17F is also found to inhibit the angiogenesis of endothelial cells and induce endothelial cells to produce IL2; TGFB1/TGFB; and monocyte chemoattractant protein-1. Defects in IL-17F are the cause of familial candidiasis type 6 (CANDF6). |
Resources
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Datasheet
Catalog Number
PKSH032623-50ug-ELS
Name
Recombinant Human Interleukin-17F/IL-17F Protein
Price(50 ug)
Pack Size