SKU: Z102645-ABM
Recombinant Human IL36RN (IL1F5)
Human
RT
Specifications
| Specification | Details |
|---|---|
| Gene Symbol | IL36RN |
| Molecular Weight | N/A |
| Source | E. coli |
| Purity | >95% as determined by SDS-PAGE |
| Format | Lyophilized Powder |
| Synonyms | IL36RN FIL1D, IL1F5, IL1HY1, IL1L1, IL1RP3, Interleukin-36 receptor antagonist protein |
| Organism | Human |
| Gene ID | 26525 |
| Background | Human IL36RN (IL1F5) is one of the cytokines from the interleukin 1 family encoded by a cluster of genes on chromosome 2. All members of this family show a 12 beta -strand, beta -trefoil configuration. IL36RN is a secreted protein monomer which is also known as interleukin 36 receptor antagonist (IL36RA). This cytokine is predominantly expressed in keratinocytes and a variety of other cell types including brain leukocytes, dendritic cells and macrophage cell types. IL36RN has shown increased expression in lesional psoriasis skin and is thought to play a role in skin inflammation. IL1F5 is a specific antagonist of the IL1 receptor related protein 2 - mediated response to IL1F9. It is also known to specifically inhibit the activation of NF-Kappa-B transcription factor which is induced by IL1F6. |
Catalog Number
Z102645-ABM
Name
Recombinant Human IL36RN (IL1F5)
Price(20 ug)
Pack Size