SKU: PKSH032918-50ug-ELS
Recombinant Human HMBS Protein (His Tag)
Human
In Stock
RT
Specifications
| Specification | Details |
|---|---|
| Molecular Weight | 40.5 kDa |
| Tag | C-6His |
| Source | Human Cells |
| Purity | > 95 % as determined by reducing SDS-PAGE. |
| Endotoxin Level | < 1.0 EU per µg as determined by the LAL method. |
| Format | Lyophilized from a 0.2 μm filtered solution of 20mM PB,150mM NaCl,pH7.4. |
| Synonyms | Porphobilinogen Deaminase; PBG-D; Hydroxymethylbilane Synthase; HMBS; Pre-Uroporphyrinogen Synthase; HMBS; PBGD; UPS |
| Organism | Human |
| Accession No. | P08397 |
| Sequence Info | Ser2-His361 |
| Background | Porphobilinogen Deaminase (HMBS) is a member of the HMBS family. PBGD is the third enzyme of the heme biosynthetic pathway and catalyzes the head to tail condensation of four porphobilinogen molecules into the linear hydroxymethylbilane. HMBS is involved in the production of heme, which is important for all of the body's organs, although it is most abundant in the blood, bone marrow, and liver. In addition, Heme is an essential component of iron-containing proteins called hemoproteins, including hemoglobin. Defects in PBGD are the cause of acute intermittent porphyria. |
Resources
PDF
Datasheet
Catalog Number
PKSH032918-50ug-ELS
Name
Recombinant Human HMBS Protein (His Tag)
Price(5000 ug)
Pack Size