SKU: RPC21314-1000-BM
Recombinant Human Fibroblast growth factor 1 (FGF1)
Human (Homo sapiens)
Blue Ice
Specifications
| Specification | Details |
|---|---|
| Molecular Weight | 31.8kDa |
| Tag | N-Terminal 6Xhis-Sumo-Tagged |
| Source | E. coli |
| Purity | >90% by SDS-PAGE |
| Endotoxin Level | Not Tested |
| Synonyms | Acidic fibroblast growth factor; aFGFEndothelial cell growth factor; ECGFHeparin-binding growth factor 1; HBGF-1 |
| Organism | Human (Homo sapiens) |
| Accession No. | P05230 |
| Sequence Info | Full Length of Mature Protein 16~155aa |
| Background | Plays an important role in the regulation of cell survival, cell division, angiogenesis, cell differentiation and cell migration. Functions as potent mitogen in vitro. Acts as a ligand for FGFR1 and integrins. Binds to FGFR1 in the presence of heparin leading to FGFR1 dimerization and activation via sequential autophosphorylation on tyrosine residues which act as docking sites for interacting proteins, leading to the activation of several signaling cascades. Binds to integrin ITGAV |
Catalog Number
RPC21314-1000-BM
Name
Recombinant Human Fibroblast growth factor 1 (FGF1)
Price(1000 ug)
Pack Size