SKU: PKSH032186-10ug-ELS
Recombinant Human CCL11/Eotaxin Protein
Human
In Stock
RT
Specifications
| Specification | Details |
|---|---|
| Molecular Weight | 8.6 kDa |
| Source | E.coli |
| Purity | > 95 % as determined by reducing SDS-PAGE. |
| Endotoxin Level | < 1.0 EU per µg as determined by the LAL method. |
| Format | Lyophilized from a 0.2 μm filtered solution of 20mM PB, 150mM NaCl，pH7.4. |
| Synonyms | Eotaxin; C-C Motif Chemokine 11; Eosinophil Chemotactic Protein; Small-Inducible Cytokine A11; CCL11; SCYA11 |
| Organism | Human |
| Accession No. | P51671 |
| Sequence Info | Gly24-Pro97 |
| Background | C-C Motif Chemokine 11 (CCL11) is a secreted protein that belongs to the intercrine beta (chemokine CC) family. In response to the presence of allergens, CCL11 selectively recruits eosinophils, a prominent feature of allergic inflammatory reactions. The effects of CCL11 are mediated by its binding to a G-protein-linked receptor known as a chemokine receptor. Chemokine receptors for CCL11 include CCR2, CCR3 and CCR5. However, it has been found that CCL11 has high degree selectivity for its receptor, such that they are inactive on neutrophils and monocytes, which do not express CCR3. |
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Datasheet
Catalog Number
PKSH032186-10ug-ELS
Name
Recombinant Human CCL11/Eotaxin Protein
Price(1000 ug)
Pack Size