SKU: PKSH033955-50ug-ELS
Recombinant Human Angiopoietin-1/ANG1 (N-Fc)
Human
RT
Specifications
| Specification | Details |
|---|---|
| Molecular Weight | 53.9 kDa |
| Tag | N-Fc |
| Source | Human Cells |
| Purity | > 95 % as determined by reducing SDS-PAGE. |
| Endotoxin Level | < 1.0 EU per µg as determined by the LAL method. |
| Format | Lyophilized from a 0.2 μm filtered solution of PBS, pH 7.4. |
| Synonyms | AGP1; AGPT; Ang1; ANG-1; angiopoietin 1; Angiopoietin-1; ANGPT1 |
| Organism | Human |
| Accession No. | Q15389 |
| Sequence Info | Asp256-Phe498 |
| Background | Angiopoietin-1 (Ang-1) is a secreted glycoprotein that plays a critical role in the development and maintenance of the vascular system. The angiopoietin (ANGPT)-TIE2/TEK signaling pathway is essential for blood and lymphatic vascular homeostasis. ANGPT1 is a potent TIE2 activator, whereas ANGPT2 functions as a context-dependent agonist/antagonist. Angiopoietin-1 can protect against pulmonary arterial hypertension, reduce the extent of fibrosis and remodeling in infarcted diabetic myocardium, and enhance tumor progression and metastasis. |
Resources
PDF
Datasheet
Catalog Number
PKSH033955-50ug-ELS
Name
Recombinant Human Angiopoietin-1/ANG1 (N-Fc)
Price(50 ug)
Pack Size