SKU: UPR-R52H3-1mg-AC
Rat uPAR / PLAUR Protein, His Tag
Rat
In Stock
RT
Specifications
| Specification | Details |
|---|---|
| Label | Unconjugated |
| Host | HEK293 |
| Molecular Weight | 32 kDa |
| Tag | C-10×His |
| Purity | 90% |
| Endotoxin Level | 1.0 EU per μg |
| Format | Powder |
| Organism | Rat |
| Accession No. | P49616-1 |
| Sequence Info | Leu 25 - Gly 299 |
| Background | This gene encodes the receptor for urokinase plasminogen activator and, given its role in localizing and promoting plasmin formation, likely influences many normal and pathological processes related to cell-surface plasminogen activation and localized degradation of the extracellular matrix. It binds both the proprotein and mature forms of urokinase plasminogen activator and permits the activation of the receptor-bound pro-enzyme by plasmin. The protein lacks transmembrane or cytoplasmic domains and may be anchored to the plasma membrane by a glycosyl-phosphatidylinositol (GPI) moiety following cleavage of the nascent polypeptide near its carboxy-terminus. However, a soluble protein is also produced in some cell types. Alternative splicing results in multiple transcript variants encoding different isoforms. The proprotein experiences several post-translational cleavage reactions that have not yet been fully defined. [provided by RefSeq, Jul 2008] |
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Catalog Number
UPR-R52H3-1mg-AC
Name
Rat uPAR / PLAUR Protein, His Tag
Price(100 mg)
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