SKU: T1309-1g-TM

Propylthiouracil

Blue Ice

Specifications

Specification	Details
Additional Information	Propylthiouracil is a thiourea derivative with an antithyroid property. Propylthiouracil (PTU) interferes with the oxidation of iodine possibly by interaction with peroxidase or a peroxidase-mediated complex reaction, thereby inhibiting synthesis of thyroid hormones tri-iodothyronine (T3) and thyroxine (T4). In addition, this agent inhibits the Type I 5'-deiodinase (D1), an enzyme involved in the peripheral conversion of thyroxine to tri-iodothyronine. This results in decreased plasma triiodothyronine concentrations and decreased entrance of thyroxine into cells thereby reducing thyroid hormone activity.
Synonyms	6-Propyl-2-thiouracil; Pseudocapsaicin; 6-n-Propylthiouracil; NSC 6498; NSC 70461

Specification

Details

Additional Information

Propylthiouracil is a thiourea derivative with an antithyroid property. Propylthiouracil (PTU) interferes with the oxidation of iodine possibly by interaction with peroxidase or a peroxidase-mediated complex reaction, thereby inhibiting synthesis of thyroid hormones tri-iodothyronine (T3) and thyroxine (T4). In addition, this agent inhibits the Type I 5'-deiodinase (D1), an enzyme involved in the peripheral conversion of thyroxine to tri-iodothyronine. This results in decreased plasma triiodothyronine concentrations and decreased entrance of thyroxine into cells thereby reducing thyroid hormone activity.

Synonyms

6-Propyl-2-thiouracil; Pseudocapsaicin; 6-n-Propylthiouracil; NSC 6498; NSC 70461

Resources

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Datasheet

Catalog Number

T1309-1g-TM

Name

Propylthiouracil

Price(1 g)

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