SKU: T33699-25mg-TM
NLCQ-1 HCl
Blue Ice
Specifications
| Specification | Details |
|---|---|
| CAS No. | 221292-08-6 |
| Additional Information | NLCQ-1 is a novel weak DNA-intercalative bioreductive compound. NLCQ-1 exhibited a C50 of 44 microM. NLCQ-1 demonstrated significant hypoxic selectivity in several rodent (V79, EMT6, SCCVII) or human (A549, OVCAR-3) tumor cell lines. Its potency as a hypoxic cytotoxin ranged between 10 and 136 microM x h, for the cell lines tested, at 30 microM input concentration. NLCQ-1 was a very potent and efficient radiosensitizer of hypoxic V79 cells, providing SER values of 2.27-2.56 at 20-80 microM concentration (measured at 10% survival level). Preclinical results suggest a possible use of NLCQ-1 as adjuvants to radiotherapy. |
| Synonyms | NLCQ1 |
| Molecular Weight | 368,22 |
| Formula | C15H15Cl2N5O2 |
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Datasheet
Catalog Number
T33699-25mg-TM
Name
NLCQ-1 HCl
Price(25 mg)
Pack Size