SKU: T69771-50mg-TM
MS-177
In Stock
Blue Ice
Specifications
| Specification | Details |
|---|---|
| Additional Information | MS177, a potent and rapid EZH2 degrader, functions as a PROTAC comprised of a CRBN ligand, linker, and a powerful enzymatic EZH2 inhibitor C24 (C24 IC50: 12 nM). It successfully targets and depletes both canonical EZH2–PRC2 and noncanonical EZH2–cMyc complexes. Furthermore, MS177 inhibits leukemia cell growth, induces apoptosis, and arrests cell cycle progression. |
| Synonyms | MS177 |
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Datasheet
Catalog Number
T69771-50mg-TM
Name
MS-177
Price(5000 mg)
Pack Size