SKU: PD2-M5254-100ug-AC
Mouse PD-L2 / B7-DC Protein, Fc Tag
Mouse
In Stock
RT
Specifications
| Specification | Details |
|---|---|
| Label | Unconjugated |
| Host | HEK293 |
| Molecular Weight | 49.2 kDa |
| Tag | C-Fc |
| Purity | 95% |
| Endotoxin Level | 1.0 EU per μg |
| Format | Powder |
| Synonyms | PDL2,PD-L2,Butyrophilin B7-DC,CD273,PDCD1 ligand 2,PDCD1L2,PDCD1LG2 |
| Organism | Mouse |
| Accession No. | NP_067371 |
| Sequence Info | Leu 20 - Arg 219 |
| Background | Programmed cell death 1 ligand 2 (PD-L2 or PDCD1 ligand 2) is also known as Butyrophilin B7-DC, CD antigen CD273, which belongs to the immunoglobulin superfamily or BTN/MOG family. The expression of PD-L2 is up-regulated by IFNG/IFN-gamma stimulation in monocytes and induced on dendritic cells grown from peripheral blood mononuclear cells with CSF2 and IL-4. PD-L2 Involved in the costimulatory signal, essential for T-cell proliferation and IFNG production in a PDCD1-independent manner. PD-L2 interaction with PDCD1 inhibits T-cell proliferation by blocking cell cycle progression and cytokine production. |
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Datasheet
Catalog Number
PD2-M5254-100ug-AC
Name
Mouse PD-L2 / B7-DC Protein, Fc Tag
Price(10000 ug)
Pack Size