SKU: ILA-M52H6-100ug-AC
Mouse IL-17 RA / CD217 Protein, His Tag (MALS verified)
Mouse
Specifications
| Specification | Details |
|---|---|
| Label | Unconjugated |
| Host | HEK293 |
| Molecular Weight | 35.2 kDa |
| Tag | C-10×His |
| Purity | 95% |
| Format | Powder |
| Organism | Mouse |
| Accession No. | Q60943 |
| Sequence Info | Ser 32 - Trp 322 |
| Background | Interleukin 17 receptor A (IL17RA) is also known as cluster of differentiation w217 (CDw217), is a pro-inflammatory cytokine secreted by activated T-lymphocytes, belong to ubiquitous type I membrane glycoprotein, and binds with low affinity to interleukin 17A (IL17A). IL 17R mRNA exhibits a broad tissue distribution, and has been detected in virtually all cells and tissues tested . IL 17RA associates with IL 17RC to form a signaling receptor complex for IL 17 and IL 17F . Ligand and IL 17RA ligation promotes T cell activation and the production of IL - 6, G-CSF, SCF, and multiple pro-inflammatory chemokines. Defects in IL17RA are the cause of familial candidiasis type 5 (CANDF5). |
Resources
PDF
Datasheet
Catalog Number
ILA-M52H6-100ug-AC
Name
Mouse IL-17 RA / CD217 Protein, His Tag (MALS verified)
Price(100 ug)
Pack Size