SKU: TF2-H5227-1mg-AC
Human TFPI-2 Protein
Human
In Stock
RT
Specifications
| Specification | Details |
|---|---|
| Label | Unconjugated |
| Host | HEK293 |
| Molecular Weight | 22.7 kDa |
| Tag | C-6×His |
| Purity | 90% |
| Endotoxin Level | 1.0 EU per μg |
| Format | Powder |
| Synonyms | TFPI2,PP5,REF1 |
| Organism | Human |
| Accession No. | NP_006519.1 |
| Sequence Info | Asp 23 - Lys 213 |
| Background | Tissue Factor Pathway Inhibitor 2 (TFPI2) is also known as placental protein 5 (PP5) and retinal pigment epithelial cell factor 1 (REF1), is a member of the Kunitz-type serine proteinase inhibitor family, is a structural homologue of tissue factor pathway inhibitor (TFPI). TFPI2 is highly abundant in the full-term placenta and widely expressed in umbilical vein endothelial cells, liver, placenta, heart, pancreas, and maternal serum at advanced pregnancy. TFPI2 may play a role in the regulation of plasmin-mediated matrix remodeling. Inhibits trypsin, plasmin, factor VIIa/tissue factor and weakly factor Xa and has no effect on thrombin. Reduced synthesis of TFPI-2 has been related to numerous pathophysiological processes such as inflammation, angiogenesis, atherosclerosis, retinal degeneration and tumor growth / metastasis. |
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Catalog Number
TF2-H5227-1mg-AC
Name
Human TFPI-2 Protein
Price(100 mg)
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