SKU: LI4-H5256-1mg-AC
Human LILRB4 / CD85k / ILT3 Protein, Fc Tag (MALS verified)
Human
In Stock
RT
Specifications
| Specification | Details |
|---|---|
| Label | Unconjugated |
| Host | HEK293 |
| Molecular Weight | 52.7 kDa |
| Tag | C-Fc |
| Purity | 95% |
| Endotoxin Level | 1.0 EU per μg |
| Format | Powder |
| Synonyms | LILRB4,ILT3,LIR5,CD85K,HM18 |
| Organism | Human |
| Accession No. | AAH26309.1 |
| Sequence Info | Gln 22 - Glu 259 |
| Background | Leukocyte immunoglobulin-like receptor subfamily B member 4 (LILRB4) is also known as CD85 antigen-like family member K (CD85K), Immunoglobulin-like transcript 3 (ILT-3), Leukocyte immunoglobulin-like receptor 5 (LIR-5), Monocyte inhibitory receptor HM18, which belongs to the leukocyte immunoglobulin-like receptor (LIR) family. LILRB4 / CD85K contains 2 Ig-like C2-type (immunoglobulin-like) domains. CD85K is detected in monocytes, macrophages, dendritic cells, lung, natural killer cells and B-cells. LILRB4 / CD85K is receptor for class I MHC antigens. CD85K recognizes a broad spectrum of HLA-A, HLA-B, HLA-C and HLA-G alleles, involved in the down-regulation of the immune response and the development of tolerance. LILRB4 interferes with TNFRSF5-signaling and NF-kappa-B up-regulation and inhibits receptor-mediated phosphorylation of cellular proteins and mobilization of intracellular calcium ions. |
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Datasheet
Catalog Number
LI4-H5256-1mg-AC
Name
Human LILRB4 / CD85k / ILT3 Protein, Fc Tag (MALS verified)
Price(100 mg)
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