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SKU: APL-H52D1-100ug-AC

Human APRIL / TNFSF13 Protein, His,Flag Tag, active trimer (MALS verified)

Human In Stock RT

Specifications

Specification Details
Label Unconjugated
Host HEK293
Molecular Weight 50.2 kDa
Tag N-10×His & N-Flag
Purity 95%
Endotoxin Level 0.01 EU per μg
Format Powder
Synonyms APRIL,TNFSF13,TALL-2,TRDL-1,CD256,TALL2,ZTNF2
Organism Human
Accession No. O75888-1
Sequence Info Gln 111 - Leu 250
Background APRIL(a proliferation-inducing ligand) is also known as Tumor necrosis factor ligand superfamily member 13, TALL-2, TRDL-1, CD256, TNFSF13, cytokine that binds to TNFRSF13B/TACI and to TNFRSF17/BCMA. APRIL is a cytokine of the tumor necrosis factor family associated mainly with hematologic malignancies. The closely related TNF family ligands B cell activation factor (BAFF) and a proliferation-inducing ligand (APRIL) serve in the generation and maintenance of mature B-lymphocytes. Both BAFF and APRIL assemble as homotrimers that bind and activate several receptors that they partially share. BAFF-APRIL heteromers of different stoichiometries have distinct receptor-binding properties and activities. In addition, expression of APRIL was regulated by miR-145 in GC cells.

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Datasheet

Catalog Number
APL-H52D1-100ug-AC
Name
Human APRIL / TNFSF13 Protein, His,Flag Tag, active trimer (MALS verified)
Price(10000 ug)
Pack Size
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