SKU: 2B4-H5255-100ug-AC
Human 2B4 / CD244 / SLAMF4 Protein, Fc Tag
Human
RT
Specifications
| Specification | Details |
|---|---|
| Label | Unconjugated |
| Host | HEK293 |
| Molecular Weight | 48.9 kDa |
| Tag | C-Fc |
| Purity | 90% |
| Endotoxin Level | 1.0 EU per μg |
| Format | Powder |
| Synonyms | CD244,2B4,SLAMF4,NKR2B4,NAIL,h2B4 |
| Organism | Human |
| Accession No. | Q9BZW8-2 |
| Sequence Info | Cys 22 - Arg 221 |
| Background | Natural killer cell receptor 2B4 is also known as NK cell type I receptor protein 2B4 (NKR2B4 or h2B4), SLAM family member 4 (SLAMF4), Signaling lymphocytic activation molecule 4, CD antigen CD244. NKR2B4 / CD244 contains two Ig-like (immunoglobulin-like) domains. CD244 is expressed in spleen, PBL, followed by lung, liver, testis and small intestine. CD244 interacts with CD48. Following phosphorylation, CD244 is able to recruit PTPN11/SHP-2 and SH2D1A/SAP. SLAMF4 modulate other receptor-ligand interactions to enhance leukocyte activation. CD244/2B4 is the only heterophilic receptor of SLAM family. |
Resources
PDF
Datasheet
Catalog Number
2B4-H5255-100ug-AC
Name
Human 2B4 / CD244 / SLAMF4 Protein, Fc Tag
Price(100 ug)
Pack Size