SKU: T69806-25mg-TM
EGIS-8332
Blue Ice
Specifications
| Specification | Details |
|---|---|
| CAS No. | 220725-87-1 |
| Additional Information | EGIS-8332 is a potent and selective non-competitive AMPA receptor antagonist. EGIS-8332 inhibits AMPA/kainate ion channels and cell death. EGIS-8332 inhibited AMPA currents in rat cerebellar Purkinje cells and inhibited the AMPA- and quisqualate-induced excitotoxicity in primary cultures of telencephalon neurons (IC(50)=5.1-9.0 microM), in vitro. EGIS-8332 seems suitable for further development for the treatment of epilepsy, ischaemia and stroke based on its efficacy in a variety of experimental disease models, and on its low side effect potential. |
| Molecular Weight | 362,389 |
| Formula | C20H18N4O3 |
Resources
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Datasheet
Catalog Number
T69806-25mg-TM
Name
EGIS-8332
Price(25 mg)
Pack Size