SKU: T70277-50mg-TM

Cynandione A

Blue Ice

Specifications

Specification	Details
Additional Information	Cynandione A is an acetophenone isolated from Cynanchum Wilfordii Radix. Cynandione A inhibit inflammation through macrophageal α7 nAChR activation and subsequent IL-10 expression. Cynandione A inhibits hepatic de novo lipogenesis by activating the LKB1/AMPK pathway in HepG2 cells. Cynandione A inhibits lipopolysaccharide-induced cell adhesion via suppression of the protein expression of VCAM‑1 in human endothelial cells. Cynandione A attenuates lipopolysaccharide-induced production of inflammatory mediators via MAPK inhibition and NF-κB inactivation in RAW264.7 macrophages and protects mice against endotoxin shock.

Specification

Details

Additional Information

Cynandione A is an acetophenone isolated from Cynanchum Wilfordii Radix. Cynandione A inhibit inflammation through macrophageal α7 nAChR activation and subsequent IL-10 expression. Cynandione A inhibits hepatic de novo lipogenesis by activating the LKB1/AMPK pathway in HepG2 cells. Cynandione A inhibits lipopolysaccharide-induced cell adhesion via suppression of the protein expression of VCAM‑1 in human endothelial cells. Cynandione A attenuates lipopolysaccharide-induced production of inflammatory mediators via MAPK inhibition and NF-κB inactivation in RAW264.7 macrophages and protects mice against endotoxin shock.

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Catalog Number

T70277-50mg-TM

Name

Cynandione A

Price(50 mg)

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