SKU: T4260-50mg-TM
Capmatinib 2HCl
Blue Ice
Specifications
| Specification | Details |
|---|---|
| Additional Information | INCB-28060(free base) is a novel, ATP-competitive inhibitor of c-MET kinase with an IC50 with 0.13 nM.INCB28060 exhibits picomolar enzymatic potency and is highly specific for c-MET with more than 10, 000-fold selectivity over a large panel of human kinases. This inhibitor potently blocks c-MET phosphorylation and activation of its key downstream effectors in c-MET-dependent tumor cell lines. As a result, INCB 28060 potently inhibits c-MET-dependent tumor cell proliferation and migration and effectively induces apoptosis in vitro. |
| Synonyms | INCB28060 2HCl; INC-280 2HCl |
| Purity | 99.80% |
Resources
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Datasheet
Catalog Number
T4260-50mg-TM
Name
Capmatinib 2HCl
Price(50 mg)
Pack Size