SKU: TL0007-1ml-TM
Bisdemethoxycurcumin
Blue Ice
Specifications
| Specification | Details |
|---|---|
| Additional Information | Bisdemethoxycurcumin (BDMC) is a natural demethoxy derivative of curcumin. It is a potent activator of macrophage phagocytosis, interacting with 1α, 25-dihydroxy vitamin D3 to stimulate amyloid-β clearance by macrophages (optimal stimulation at 100 nM BDMC) [1]. More stable than curcumin in physiological media, BDMC suppresses proliferation of cancer cells [2]. It down-regulates the transcriptional coactivator p300, suppressing the Wnt/β-catenin pathway, and inhibits LPS induction of iNOS expression [3]. |
| Synonyms | Didemethoxycurcumin; Curcumin III |
| Purity | 99.34% |
Resources
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Datasheet
Catalog Number
TL0007-1ml-TM
Name
Bisdemethoxycurcumin
Price(1 ml * 10 mM (in DMSO))
Pack Size