SKU: FC4-M82E8-25ug-AC
Biotinylated Mouse Fc gamma RIV / CD16-2 Protein, His,Avitag™ (BLI verified)
Mouse
In Stock
RT
Specifications
| Specification | Details |
|---|---|
| Label | Biotin-labeled |
| Host | HEK293 |
| Molecular Weight | 24.6 kDa |
| Tag | C-10×His & C-Avi |
| Purity | 90% |
| Format | Powder |
| Synonyms | Fc gamma RIV,CD16-2,Fcgr4 |
| Organism | Mouse |
| Accession No. | A0A0B4J1G0-1 |
| Sequence Info | Gly 21 - Gln 203 |
| Background | FcgR4(Low affinity immunoglobulin gamma Fc region receptor IV) is also known as CD16-2, FcgammaRIV, receptor for the Fc region of immunoglobulin gamma . Also acts as a receptor for the Fc region of immunoglobulin epsilon . Binds with intermediate affinity to both IgG2a and IgG2b . Does not display binding to IgG1 or IgG3. Plays a role in promoting bone resorption by enhancing osteoclast differentiation following binding to IgG2a. Binds with low affinity to both the a and b allotypes of IgE. Has also been shown to bind to IgE allotype a only but not to allotype b. Binding to IgE promotes macrophage-mediated phagocytosis, antigen presentation to T cells, production of proinflammatory cytokines and the late phase of cutaneous allergic reactions |
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Catalog Number
FC4-M82E8-25ug-AC
Name
Biotinylated Mouse Fc gamma RIV / CD16-2 Protein, His,Avitag� (BLI verified)
Price(2500 ug)
Pack Size