SKU: HL0-H82E8-200ug-AC
Biotinylated Human HLA-E*01:03&B2M&CMV UL40 (VMPPRTVIL) Complex Protein (Monomer, MALS verified)
Human
RT
Specifications
| Specification | Details |
|---|---|
| Label | Biotin-labeled |
| Host | HEK293 |
| Molecular Weight | 36.2 kDa and 13.8 kDa |
| Tag | C-10×His & C-Avi |
| Purity | 95% |
| Format | Powder |
| Organism | Human |
| Accession No. | P13747 (HLA-E*01:03) & P61769-1 (B2M) & VMPPRTVIL |
| Sequence Info | Gly 22 - Ile 305 (HLA-E*01:03) & Ile 21 - Met 119 (B2M) & VMPPRTVIL peptide |
| Background | HLA-E belongs to the HLA class I heavy chain paralogues. This class I molecule is a heterodimer consisting of a heavy chain and a light chain (beta-2 microglobulin). The heavy chain is anchored in the membrane. HLA-E binds a restricted subset of peptides derived from the leader peptides of other class I molecules. The heavy chain is approximately 45 kDa and its gene contains 8 exons. Exon one encodes the leader peptide, exons 2 and 3 encode the alpha1 and alpha2 domains, which both bind the peptide, exon 4 encodes the alpha3 domain, exon 5 encodes the transmembrane region, and exons 6 and 7 encode the cytoplasmic tail. |
Resources
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Datasheet
Catalog Number
HL0-H82E8-200ug-AC
Name
Biotinylated Human HLA-E*01:03&B2M&CMV UL40 (VMPPRTVIL) Complex Protein (Monomer, MALS verified)
Price(200 ug)
Pack Size