SKU: T6242-GVO-ABM
EDC4 Stable Expressing HEK293T Cell Line
Human
Dry Ice
Specifications
| Specification | Details |
|---|---|
| Organism | Human |
| Additional Information | EDC4 plays a key role in homologous recombination by stimulating end resection at double-strand breaks. EDC4 deficiency leads to genome instability and hypersensitivity to DNA interstrand crosslinking drugs and PARP inhibitors. Lack-of-function mutations in EDC4 were detected in BRCA1/2-mutation-negative breast cancer cases, suggesting a role in breast cancer susceptibility. |
Catalog Number
T6242-GVO-ABM
Name
EDC4 Stable Expressing HEK293T Cell Line
Price(1 x 10^6 cells)
Please inquire
Pack Size
1 x 10^6 cells