8-Bromoguanosine-5'-O-triphosphate sodium
Specifications | |
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Formula: | C10H11BrN5O14P3.4Na |
Molecular Weight: | 690 |
Description
8-Bromoguanosine-5'-O-triphosphate, a derivative of guanosine 5'-triphosphate (GTP) - the energy substrate for protein synthesis and gluconeogenesis, acts as an inhibitor of the E. coli GTPase FtsZ with an inhibition constant (Ki) of 31.8 µM. Furthermore, at a concentration of 500 µM, it facilitates the assembly of porcine brain microtubules in a cell-free assay.
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