AV123
| Specifications | |
|---|---|
| CAS Number: | 233605-81-7 |
| Formula: | C11H14N4O2 |
| Molecular Weight: | 234,25 |
Description
AV123 (compound 12) is a non-cytotoxic RIPK1 inhibitor with IC 50 of 12.12 μM. AV123 blocks the TNF-α-induced necroptotic with EC 50 of 1.7 μM, but not the apoptotic cell death. AV123 can be used in the study of necrotic chronic conditions such as ischemia-reperfusion injury of the brain, heart and kidney, inflammatory diseases, neurodegenerative diseases and infectious diseases [1].
Price
1.522,00 €
