3-D Life RGD Peptide

Matrix-bound adhesion peptides may confer cellular adhesion to the hydrogel matrix, which is a prerequisite for cellular growth, differentiation and survival of many cell types

Product Description

RGD sequences are motifs on extracellular matrix proteins promoting adhesion to cellular integrin receptors. The 3-D Life RGD Peptide contains a RGD motif and a thiol group on the N-terminus. The thiol group is used to immobilize the peptide on thiol-reactive polymers in 3-D Life Hydrogels. The immobilized peptide promotes adhesion of cells carrying the appropriate integrin receptor.

For instuctions please consult General Protocol GP-1 "Preparation of 3-D Life Fast Gelling Hydrogels" or General Protocol GP-2 "Preparation of 3-D Life Slow Gelling Hydrogels".

Application

Modification of 3-D Life Hydrogels with cell-adhesive properties. 3-D cell culture of cells requiring a cell-adhesive matrix based on the RGD motif.

Peptide Sequence

Acetyl-Cys-Doa*-Doa-Gly-Arg-Gly-Asp-Ser-Pro-NH2
*: Doa:8-amino-3,6-dioxaoctanoic acid

Molar Mass

1022 g/mol

Purity

>90% (HPLC)