NanoString GeoMx Digital Spatial Profiling Service

Combine the best of spatial and molecular profiling technologies by spatially profiling digital whole transcriptomes, cancer transcriptomes and profiling data for 100s of validated proteins

Product Description

Reliably and quantitatively assess the heterogeneity within your tissue samples with a combination of the most flexible, nondestructive, and robust high-plex and high-throughput spatial solution. BioChain uses the NanoString GeoMx^®Digital Spatial Profiling platform to measure patterns of gene expression in specific targeted areas of interest.

Any Target - answer new questions with the Whole Transcriptome Atlas and the extensive catalog of validated protein assays
Any Region - explore true biology with flexible region of interest strategies
Any Sample - spatially profile even the most challenging sample types including FFPE, TMAs, and Fresh Frozen with no DV200% prequalification

GeoMx Digital Spatial Profiling Workflow

The GeoMx DSP workflow seamlessly integrates with current histology methods to get you robust and reproducible spatial omics data quickly.

Bc Spatial Profiling Geomx Workflow

Tunable Dynamic Profiling Modalities

Explore true biological questions with flexible region of interest (ROI) strategies. ROI selection is based on tissue morphology which allows researchers to precisely select which tissue compartments or cell types they want to profile. BioChain's team of spatial multiomics experts work side by side with researchers to assist them in the ROI selection process and aim to address all questions or concerns.

Spatial Profiling Profiling Modalities

Profiling Panels

Human Whole Transcriptome Atlas (WTA)

The GeoMx Human Whole Transcriptome Atlas allows researchers in oncology, immunology, neuroscience, developmental biology, and other diverse fields to break barriers and unlock new pathways. NanoString’s WTA panel is an apt solution for transcriptome interrogation. With 18,000+ human targets and 21,000+ mouse targets, these panels help researchers explore new pathways to be explored and enable profiling in oncology, immunology, neuroscience, and developmental biology. View detailed Bulletin.

Cancer Transcriptome Panel (CTA)

Designed for an all-inclusive profiling of tumor biology, the tumor microenvironment, and the immune response, the GeoMx Cancer Transcriptome Atlas is a research catalyst for the comprehensive coverage of cancer biology. View detailed Bulletin.

Mouse Whole Transcriptome Atlas (Mouse WTA)

Understand the tissue architecture and the underlying functions of mouse models to advance research in developmental biology, disease onset, progression, treatment, and much more. View detailed Bulletin.

GeoMx Protein Assays

Break free of the traditional immunohistochemical methods that limit the number of markers you can profile from a single tissue section. GeoMx DSP allows for High-plex Spatial Proteomic Analysis of 96+ proteins, with all assays validated for use in multiplex, saving researchers the headaches associated with troubleshooting assay performance. View detailed Bulletin.

GeoMx Data Suite

Data discovery, visualization, analysis, and publishing have never been easier with the GeoMx DSP data suite. A fully end-to-end integrated solution provides researchers with all the tools to track image data and profiling data, enabling an efficient workflow from data collection to data analysis.

Side by side consulting with BioChain’s expert digital multiomics scientists to address all questions, comments, or concerns
Optimized data algorithms for automatically segmenting based on morphology markers
Integrated statistical tools to detect changes between groups (e.g. t-tests, linear mixed models) or to see outliers
Effortless visualizations of large data matrices
Rapidly visualize whole tissue sections at single cell resolutions and automate ROI selection to streamline the workflow
Built-in quality control assessments for data validation
High quality figures and images ready for publications

Resources

GeoMx Detailed Brochure
GeoMx Digital Spatial Profiler Overview
Guidelines for Choosing Morphology Markers