Rabbit IgG Antibody, CUTANA™ CUT&RUN Negative Control

CUTANA^™ CUT&RUN kits, reagents, and assay services map histone PTMs and chromatin-interacting proteins with high resolution, at a fraction of the time and cost of standard ChIP-seq experiments.

Product Description

This Rabbit IgG Antibody can be used to control for non-specific background signal in CUT&RUN and other applications. A positive control antibody is also available (Histone H3K4me3 CUT&RUN Positive Control Antibody).

Figure 1. Heatmap for Rabbit IgG CUT&RUN negative control antibody (left) compares to Histone H3K4me3 CUT&RUN positive control antibody (right). Signal from 2.2 and 3.9 million paired-end reads, repectively, are aligned to the transcription start site (TSS, +/- 2kb) of 18,793 genes. High and low signal are ranked by intensity (top to bottom) and reflected by red and blue colors, respectively.

CUT&RUN data was generated using the EpiCypher CUTANA™ CUT&RUN protocol  and determined to yield peaks that show a genomic distribution pattern consistent with reported function(s) of the target protein.