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RNA Methylase & Demethylase Activity

RNA m6A Methylase and Demethylase Activity Assays

N6-methyladenosine (m6A) is the most common and abundant modification on RNA molecules present in eukaryotes

BioCat offers kits for measuring total m6A demethylase activity/inhibition using nuclear extracts or purified m6A demethylases like FTO and ALKBH5 from a broad range of species. 

 

M6a Methylation

Fig.1. Reversible m6A methylation in DNA/RNA