Subcellular Localisation Vectors

Subcellular localisation vectors for targeting fluorescent proteins to specific organelles

When you need a fluorescent protein or transgene targeted to a specific organelle (nucleus, mitochondria, ER, Golgi, peroxisome, plasma membrane), expression vectors with built-in targeting signals do it. Useful for cell biology imaging, organelle-targeted protein function studies, and visualising compartment-specific events.

Pick by target compartment.

1. Target. Mitochondrial targeting sequence for mitochondria. NLS for nucleus. KDEL for ER retention. Other signals for specific compartments.
2. Reporter format. Fluorescent protein for live imaging. Luciferase for biochemical readout.
3. Cell-type validation. Validate the targeting signal in your specific cell type. Promiscuous localisation in some cell types is documented.
4. Co-expression. For dual-organelle co-localisation studies match the spectral compatibility.
5. Selection marker. Match to your stable line workflow.

SBI System Biosciences is the primary supplier in this inventory.