Hi-C library prep for genome-wide chromatin contact maps and 3D genome organisation
When you need genome-wide chromatin contact maps, Hi-C library prep performs proximity ligation followed by sequencing library construction. The output reveals 3D genome organisation. Standard in reference genome construction, structural variant detection, and 3D genome research.
Pick by sample and resolution.
- Restriction enzyme. 4-cutter for higher resolution. 6-cutter for cost efficiency. Restriction-enzyme-free MNase variants.
- Sample type. Cell lines, fresh tissue, FFPE each have specific protocols. FFPE Hi-C is now mature.
- Downstream resolution. Sequencing depth scales with resolution. 100M reads for compartment-level. Billions for loop-level.
- Use case. For new Hi-C labs use a commercial kit with validated pipeline; in-house Hi-C has a steep learning curve.
Arima supplies the Arima-HiC platform in this inventory.
Contact BioCat
Questions? We are here to help. Sales, orders, and general inquiries.
Reach our team for quotes, order status, shipping questions, or anything else related to working with BioCat. We typically respond within one business day.
