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Glycobiology Arrays

Lectin and Glycan Arrays for Glycosylation Profiling and Carbohydrate-Binding Screening

Lectin and glycan arrays for glycosylation profiling and carbohydrate-binding screening

Lectin arrays, glycan arrays, and Glycome Arrays give you three ways to profile glycosylation and screen carbohydrate-binding protein interactions at scale. Lectin arrays immobilise panels of lectins with defined carbohydrate specificities on a solid support, and fluorescently labelled glycoprotein samples bind according to their surface glycan composition to produce a binding profile. Glycan arrays take the complementary approach, printing defined carbohydrate structures to capture glycan-binding proteins such as lectins, antibodies, or pathogens from solution. Both formats support glycoprotein biomarker discovery, glycosylation changes during disease or drug treatment, and host-pathogen carbohydrate interactions.

Pick by content and quantification.

  1. Glycan content. Broad survey arrays of 500+ glycans for de novo specificity. Focused panels for specific glycan classes.
  2. Readout. Fluorescence with labelled probe. Chemiluminescence for low-input samples.
  3. Sample. Verify your sample type (purified protein, serum, supernatant) is supported.
  4. Quantification. Semi-quantitative reference-based; absolute binding-affinity requires orthogonal SPR or ITC.
  5. Confirmation. After array discovery confirm hits by orthogonal binding methods before publishing specificity claims.

RayBiotech supplies glycan arrays in this inventory.

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